Every protein that's made starts with methionine. The 'methionine is bad for aging' study was flawed as it used synthetic high-deuterium methionine; the deuterium caused the harm. Cancer as a signal of mitochondria stealing methyls off of the DNA due to too much deuterium Tristan Scott: "I've listen to these biohackers. […] They eat animal based, they eat meat, but they would always be like, 'Well, there is one caveat. Methionine has been shown to be bad for aging […]'" Dr. Stephanie Seneff: "Can I talk about that there? Because I have a very good story for that." […] "I remember years ago reading about this methionine deficiency idea to try to live longer, and I was like, 'That is just so wild, so crazy. How can that possibly be true?' I was blown away by it. That just doesn't make any sense, because methionine is extremely important. It's like every protein that's made starts with methionine. It's how you start the protein synthesis. How could deficiency be a good thing? Just recently I had the idea because methionine of course is the source of methyl groups. This can get us into the deuterium big time." […] "It turns out the gut microbes are responsible for making this methyl CH₃, which has these three Hs that are not deuterium. They're like almost guaranteed not to be deuterium because of what the microbes do. So they become very important to the body, the CH₃ that's attached to the sulfur of the methionine amino acid. Then that CH₃ becomes the methyl groups that get distributed throughout your body, stuck onto your protein, stuck onto your DNA, your RNA. It's like thrown around everywhere in the body and they hold on to it. Then eventually it gets metabolized in place, like from the DNA, that methyl gets metabolized and turned into carbon dioxide and water within the mitochondria. "Those Hs get delivered to the mitochondria, Hs that are guaranteed not to be deuterium, and so that becomes very valuable to the body. It's actually storing all these methyls as a resource for when the mitochondria become toxic because they've got too much deuterium, they need to have a really good source of a guaranteed food that's going to be healthy, they can grab the methyls off the DNA. Eventually if they grab enough of them the DNA becomes deficient in methyls, and now you've got cancer, because that's how the clue for cancer, you know, many of the cancers are a consequence of hypomethylated DNA. The DNA has been losing its methyls, and that's like the cell is saying, 'Hey, my DNA is losing its methyls. We probably have a deuterium problem here.' It's like a signal that there's a deuterium problem, because it's had to steal the methyls from the DNA. "So they had this study on these rats and they fed them a synthetic diet. They were given amino acids that were produced in the laboratory. It was explained in the paper. So the rats were given all these equal appropriate amounts of all the different amino acids to eat. That's their food. It's very highly synthetic. It was made in the chemistry lab. So they gave the control group lots of methionine and then the treatment group low methionine. So that's your low methionine diet. They showed that the rats that got the low methionine diet lived longer and were healthier. So then they said, 'Well of course then methionine is bad.' Right? "The flaw is that that methionine that those rats ate was not guaranteed to have low deuterium in its methyl groups. It was made in a chemistry lab. So those methyl groups were not gold at all; they were just crap, so to speak. They were not healthy food. But on the other hand they had methionine so they weren't inspired to make methionine because it was already plenty. So they were basically misled into thinking that methionine was perfectly healthy, the way it would normally be if it had been made biologically. But because it was made in the chemistry lab it didn't have the low deuterium. So these rats are all saving all this methyl groups and being careful to keep track of them, but those methyls are no good, because they came from the synthetic laboratory instead of from a biological source." Dr. Stephanie Seneff with npub1yd2h2lrwchshvm46jq7auh65tjkxmgnapkavh7tjtqq07kknupxsa980tv @ 54:03–57:48 (posted 2023-12-05) https://youtu.be/LaU2i0T5FWY&t=3243