Glyphosate damages gut microbiota, raises gut pH, damages acid-loving microbes' ability to make butyrate. The colonocytes lining the gut get sick from a lack of butyrate, which leads to IBD and eventually colon cancer Tristan Scott: "Yeah, I think it's incredible, and that's one of the main mechanisms or areas that people are pretty familiar with is that [glyphosate] is like a nuke for your gut, really. But when you get into how it works and then how something I realized is just how important the gut is for producing things like B vitamins. I think you said in your book that it augments the the dietary intake of it. So that's something that especially folks in the diet community pretty much never talk about, and that care we need to have for our microbiota and just how the diversity has been just decreasing tremendously over decades. If you look at like studies comparing the Hadza in Africa and Tanzania compared to the modern man, it's so crazy." Dr. Stephanie Seneff: "I think I talk about that in my book. I have a chapter on the gut which I've spent a long time on it. The gut is a hard problem when you start looking. The research literature has blossomed. There's tons of papers now, and they're very complex with all these pretty colors, and all these Venn diagrams, and all these different microbes in different amounts, and it's extremely overwhelming. But I eventually dug a story out of that I feel that I'm quite confident about which is super interesting. "Glyphosate causes the pH of the gut to go up, and I think that's because of these undigested peptides. Normally the proteins come in, they get broken down into the amino acids, they get absorbed in the midgut, they get absorbed into the system, and now everybody's happy, because you need those amino acids to make human proteins. "But they don't get digested. They end up in the lower gut still as peptide sequences. And then there's gut microbes there that can break them down, but break them down all the way, because you can no longer absorb those amino acids. They have to be broken down all the way to nitrogen, which is going to be ammonia, which is going to be a high pH. So you raise the pH of the gut, and then that causes the acid-loving microbes to get sick they can't really live in this high pH. Those are the ones that make the acetate, the butyrate, the propionate. These are short-chain fatty acids that are incredibly important for the host, because the colonocytes lining the gut, their main food is butyrate, and butyrate comes from these acid-loving bacteria. And so when they can't make the butyrate, the colonocytes get sick, and then you end up with inflammatory bowel disease and irritable bowel disease, and eventually you get you know colon cancer and things like that, all of which are going up dramatically in step with the rising glyphosate usage in this country." Dr. Stephanie Seneff with npub1yd2h2lrwchshvm46jq7auh65tjkxmgnapkavh7tjtqq07kknupxsa980tv @ 26:21–28:49 (posted 2023-12-05) https://youtu.be/LaU2i0T5FWY&t=1581