I feel like gnome is very polarizing. You either really love it or you really hate it. I'm one of those people who really loves it, but I've definitely talked to a lot of people who absolutely cannot stand it.
The other environment I like is Cinnamon, but even they have some accessibility issues with screen reader. Like the applications like the file manager and stuff like that seem to work properly. But then the shell itself that has like the taskbar and the menu and stuff like that does not work.